What can potentially cause malabsorption leading to short-bowel syndrome?

Malabsorption leading to short-bowel syndrome occurs when a significant portion of the small intestine is removed or becomes dysfunctional, resulting in the inability to absorb nutrients effectively. Intestinal resection, which involves surgically removing a segment of the intestine, directly decreases the surface area available for nutrient absorption. When more than two-thirds of the small intestine is removed, it can result in short-bowel syndrome, where the patient experiences inadequate absorption of carbohydrates, proteins, fats, vitamins, and minerals.

Other factors listed may contribute to digestive issues or symptoms that could resemble those of malabsorption but do not cause short-bowel syndrome in the same definitive way. Chronic diarrhea can lead to nutrient loss but does not necessarily involve structural changes to the intestine. Adhesion formation can cause bowel obstructions or complications but is not a direct cause of short-bowel syndrome. Fiber loss primarily affects bowel movements and gastrointestinal health but lacks a direct correlation to the structural integrity needed for proper nutrient absorption.